Zetia
































Zetia is not advised in individuals with moderate to serious hepatic disability [view Precautions and warnings (5.4) and also Scientific Pharmacology (12.



Zetia offered concomitantly regarding a statin is contraindicated in clients regarding active liver illness or unusual consistent altitudes of hepatic transaminase degrees [view Contraindications (4); Precautions as well as warnings (5.2) and also Clinical Pharmacology (12.



In medical researches, administration of ezetimibe, 50 mg/day to 15 healthy and balanced subjects for as much as 14 days, 40 mg/day to 18 patients regarding main hyperlipidemia for around 56 days, as well as 40 mg/day to 27 patients regarding homozygous sitosterolemia for 26 weeks was usually well allowed. One women patient with homozygous sitosterolemia took an unintentional overdose of ezetimibe 120 mg/day for 28 days without any stated medical or laboratory adverse events.



Zetia (ezetimibe) is in a course of lipid-lowering substances that uniquely inhibits the digestive tract absorption of cholesterol levels and associated phytosterols. The chemical name of ezetimibe is 1 - (4 - fluorophenyl) - 3(R) - [3 - (4 - fluorophenyl) - 3(S) - hydroxypropyl] - 4(S) - (4 - hydroxyphenyl) - 2 - azetidinone. The observational formula is C24H21F2NO3. Its molecular weight is 409.4 and its structural formula is.



Ezetimibe is a white, crystalline powder that is openly to extremely dissolvable in ethanol, methanol, and also acetone as well as virtually insoluble in water. Ezetimibe has a melting factor of regarding 163 ° C and also is stable at ambient temperature level. Zetia is available as a tablet for oral management containing 10 mg of ezetimibe and the complying with inactive substances: croscarmellose salt NF, lactose monohydrate NF, magnesium stearate NF, microcrystalline cellulose NF, povidone USP, and also salt lauryl sulfate NF.

  • Zetia